Minggu, 18 September 2011

Monoclonal Antibody - Alternatives for Treating Non-Hodgkin's Lymphoma



Non-Hodgkin's lymphoma, or NHL is a serious love, which is due to the presence of B cells (B lymophocytes), a type of white blood cells that usually lead to severe complications such as tumors. Although, treatment with chemotherapy and radiation are considered effective for many people who suffer from the NHL, on the other hand for many pantients these procedures can be very toxic.

In addition, experts have developed in the laboratories of the new Theraphy for the treatment of NHL, Theraphy known as monoclonal antibodies, which has proven to be safe and effective for some patients. As we know the body produces antibodies, substances that play a role in the fight against bacteria and viruses. Moreover, monoclonal antibodies are produced in laboratories as well as many other antibodies and play a role in the production of anti-tumor effects. Because most B cell NHL patients, treatment with monoclonal antibodies, has brought significant results in treating lymphoma and many more are prescribed with other toxins or radioactive particles that can usually kill the cells.

In addition, monoclonal antibody treatments typically include medications like Rituxan and Bexxar. First of all, the treatment with Rituxan considered very effective for people suffering from NHL and can be used for other types of lymphomas too. Rituxan is the only monoclonal antibody approved for the treatment of NHL and most of the time he studied in patients who returned low-grade NHL. Moreover, it can be taken without other drugs, usually given intravenously once weekly for 4 weeks. Unlike other procedures, Rituxin offers no serious side effects such as hair loss, vomiting and low blood counts.

Second, there is a monoclonal antibody that is being tested in the laboratories of the Bexxar. This drug is a murine monoclonal antibody, and no naked form, because of the presence radiocative iodine molecule that is attached. Like Rituxan, this agent was administered during the first intravenous dose of a trace amount of radioactivity and the second dose, which contains most of the radioactive iodine. On the other hand, Bexxar has some negative aspects, such as fever, chills or shaking, and, in some cases of NHL patients May have a temporary drop in blood counts.

Third, another monoclonal antibody which has been studied as a treatment of NHL is Oncolym. This tool has been studied in radiolabeled form, such as Bexxar and showed up as well as other toxic radiolabeled antibodies. In contrast, the LL2 is a humanized antibody, using the naked form of unlabeled and radiolabeled form.

In conclusion, monoclonal antibodies can be very effective in the treatment of NHL because of its low toxicity and the advantage of combining them together and using them in combination with chemotherapy or other treatment. It is important to say that people who suffer from the NHL should be aware of their condition and become well informed in order to follow the treatment.

Tidak ada komentar:

Posting Komentar