What is Burkitt's Lymphoma?

Burkitt's lymphoma is a type of aggressive B-cell lymphoma. This condition is most often seen in young people and is divided into three types:

- endemic - this is commonly seen in children living in Africa. Usually, this type of Burkitt's lymphoma affects facial bones, such as forks, hoses, such as the distal ileum and blind. Other parts of the abdomen such as the ovaries and kidneys may also be affected.

- Sporadic / Non-African -. Found outside of Africa and affects the same parts as the endemic variety

- Immunodeficiency connected - this type of Burkitt's lymphoma is usually seen in HIV-infected patients or patients who are taking immune suppression drugs,

In addition to these factors are linked, Burkitt's lymphoma is highly associated with Epstein-Barr virus and malarije.Virus create mutations within the B-cells, the type of cells found in the immune system. Exposure to Malaria weakens the cell resistance to viruses, making it one of the dominant forms of non-Hodgkin's lymphoma in African children.

Usually, swollen lymph nodes can be seen in the neck area that can quickly spread to other lymph nodes through lymphatic cirkulacija.Čvorovi are more than 10 cm, and can cause obstruction and deformacija.Čvorovi are rubbery and non-tender. Since it is an aggressive type of NHL, Burkitt's lymphoma can spread easily through the nervous system and can cause weakness and paralysis. Other symptoms include fatigue, loss of appetite, night sweats, unexplained fever and weight loss. Malignant disease in certain parts of the body can affect organ function. For example, if the lymphoma is located in the spleen, anemia can lead to the ability of the spleen to store red blood cells are affected.

treatment of Burkitt's lymphomas usually involves chemotherapy agents such as Cytoxan, methotrexate and oncovin. Aggressive therapy is often shown promising effects on children, but close monitoring of renal system is required. This system can be damaged and chemotherapeutics and the occurrence of tumor lysis sindroma.Glavni goal of treatment is to prevent to prevent the further spread of the disease in the nervous system. When the proper treatment is given, the survival rate of 90% guaranteed. It is important to be subjected to the processing of a Burkitt's lymphoma is confirmed for this condition deteriorates rapidly, and life-threatening.